MORF4L2 antibody (C-Term)

Catalog No. ABIN2798726

Product Details anti-MORF4L2 Antibody

Target: MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))

Binding Specificity: AA 259-288, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MORF4L2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human MORF4L2 (C-term) Antibody

Immunogen: This MORF4L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-288 amino acids from the C-terminal region of human MORF4L2.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000MORF4L2 Antibody (C-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for MORF4L2

Target: MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))

Alternative Name: MORF4L2 (MORF4L2 Products)

Background:

Target Description: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.

Gene Symbol: MORF4L2

Molecular Weight: 32308 Da

Gene ID: 9643

UniProt: Q15014

Pathways: Regulation of Muscle Cell Differentiation