TADA3L antibody (C-Term)

Catalog No. ABIN2798740

This Rabbit Polyclonal antibody specifically detects TADA3L in WB and IF. It exhibits reactivity toward Human.

Quick Overview for TADA3L antibody (C-Term) (ABIN2798740)

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TADA3L antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-TADA3L Antibody

Binding Specificity: AA 386-414, C-Term

Purpose: Rabbit Anti-Human TADA3L (C-term) Antibody

Immunogen: This TADA3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-414 amino acids from the C-terminal region of human TADA3L.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IF: 1:10-50TADA3L Antibody (C-term) . TADA3L immunoreactivity is localized to Nucleus significantly.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for TADA3L

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Alternative Name: TADA3L

Background:

Target Description: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq].

Gene Symbol: TADA3

Molecular Weight: 48902 Da

Gene ID: 10474

UniProt: O75528

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway