PDZK1 antibody (Center)

Catalog No. ABIN2798783

The Rabbit Polyclonal anti-PDZK1 antibody has been validated for WB and IHC. It is suitable to detect PDZK1 in samples from Human.

Quick Overview for PDZK1 antibody (Center) (ABIN2798783)

Target: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDZK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PDZK1 Antibody

Binding Specificity: AA 196-224, Center

Purpose: Rabbit Anti-Human PDZK1 (Center) Antibody

Immunogen: This PDZK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human PDZK1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50PDZK1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.350 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for PDZK1

Target: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Alternative Name: PDZK1

Background:

Target Description: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).

Gene Symbol: PDZK1

Molecular Weight: 57129 Da

Gene ID: 5174

UniProt: Q5T2W1