TNNI2 antibody (N-Term)

Catalog No. ABIN2798893

This Rabbit Polyclonal antibody specifically detects TNNI2 in WB. It exhibits reactivity toward Human.

Quick Overview for TNNI2 antibody (N-Term) (ABIN2798893)

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNNI2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNNI2 Antibody

Binding Specificity: AA 1-30, N-Term

Purpose: Rabbit Anti-Human TNNI2 (N-term) Antibody

Immunogen: This TNNI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TNNI2.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of lysate from human skeletal muscle tissue lysate, using TNNI2 Antibody (N-term) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 μg per lane.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for TNNI2

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Alternative Name: TNNI2

Background:

Target Description: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].

Gene Symbol: TNNI2

Molecular Weight: 21339 Da

Gene ID: 7136

UniProt: P48788