CD86 antibody (C-Term)

Catalog No. ABIN2798923

This Rabbit Polyclonal antibody specifically detects CD86 in WB. It exhibits reactivity toward Human.

Quick Overview for CD86 antibody (C-Term) (ABIN2798923)

Target: CD86

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD86 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD86 Antibody

Binding Specificity: AA 269-298, C-Term

Purpose: Rabbit Anti-Human CD86 (C-term) Antibody

Immunogen: This CD86 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human CD86.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000CD86 Antibody (C-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for CD86

Target: CD86

Alternative Name: CD86

Background:

Target Description: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq].

Gene Symbol: CD86

Molecular Weight: 37682 Da

Gene ID: 942

UniProt: P42081

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation