Asialoglycoprotein Receptor 1 antibody (N-Term)

Catalog No. ABIN2798934

This anti-Asialoglycoprotein Receptor 1 antibody is a Rabbit Polyclonal antibody detecting Asialoglycoprotein Receptor 1 in WB. Suitable for Human.

Quick Overview for Asialoglycoprotein Receptor 1 antibody (N-Term) (ABIN2798934)

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Asialoglycoprotein Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Asialoglycoprotein Receptor 1 Antibody

Binding Specificity: AA 1-30, N-Term

Purpose: Rabbit Anti-Human ASGR1 (N-term) Antibody

Immunogen: This ASGR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ASGR1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000ASGR1 Antibody (N-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Alternative Name: ASGR1

Background:

Target Description: Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Gene Symbol: ASGR1

Molecular Weight: 33186 Da

Gene ID: 432

UniProt: P07306

Pathways: Thyroid Hormone Synthesis