FAM36A antibody (AA 51-118) (AbBy Fluor® 594)

Catalog No. ABIN2813081

This anti-FAM36A antibody is a Rabbit Polyclonal antibody detecting FAM36A in IF (cc) and IF (p). Suitable for Human.

Quick Overview for FAM36A antibody (AA 51-118) (AbBy Fluor® 594) (ABIN2813081)

Target: FAM36A (Family with Sequence Similarity 36, Member A (FAM36A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM36A antibody is conjugated to AbBy Fluor® 594

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FAM36A Antibody (AbBy Fluor® 594)

Binding Specificity: AA 51-118

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM36A

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAM36A

Target: FAM36A (Family with Sequence Similarity 36, Member A (FAM36A))

Alternative Name: FAM36A

Background:

Synonyms: FAM 36A, Family with sequence similarity 36 member A, FLJ43269, Hypothetical protein LOC116228, OTTHUMP00000038200, Protein FAM36A.

Background: FAM36A is a multi-pass membrane protein. It belongs to the FAM36 family. The exact function of FAM36A remains unknown.Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The FAM36A gene product has been provisionally designated FAM36A pending further characterization.

Gene ID: 116228