ADRP antibody (N-Term)

Catalog No. ABIN283919

The Mouse Monoclonal anti-ADRP antibody has been validated for WB, IHC (p) and IHC (fro). It is suitable to detect ADRP in samples from Human. There are 4+ publications available.

Quick Overview for ADRP antibody (N-Term) (ABIN283919)

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADRP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: AP125

Product Details anti-ADRP Antibody

Binding Specificity: AA 5-27, N-Term

No Cross-Reactivity: Cow (Bovine), Mouse (Murine)

Cross-Reactivity (Details): Dog, human, rat. No reactivity with bovine and mouse.

Immunogen: ADRP antibody was raised in mouse using a synthetic peptide corresponding to residues 5-27 from N-terminus of human adipophilin as the immunogen.

Isotype: IgG1

Application Details

Application Notes: IHC-F: 1:10
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in dist. water (final solution contains 0.09 % NaN3, 0.5 % BSA in PBS buffer, pH 7.4)

Concentration: Lot specific

Buffer: Lyophilized.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

References for anti-ADRP antibody (ABIN283919)

Arumugam, Talawar, Listenberger, Donohue, Osna, Kharbanda: "Role of Elevated Intracellular S-Adenosylhomocysteine in the Pathogenesis of Alcohol-Related Liver Disease." in: Cells, Vol. 9, Issue 6, (2020) (PubMed).

Listenberger, Townsend, Rickertsen, Hains, Brown, Inwards, Stoeckman, Matis, Sampathkumar, Osna, Kharbanda: "Decreasing Phosphatidylcholine on the Surface of the Lipid Droplet Correlates with Altered Protein Binding and Steatosis." in: Cells, Vol. 7, Issue 12, (2018) (PubMed).

Rasineni, McVicker, Tuma, McNiven, Casey: "Rab GTPases associate with isolated lipid droplets (LDs) and show altered content after ethanol administration: potential role in alcohol-impaired LD metabolism." in: Alcoholism, clinical and experimental research, Vol. 38, Issue 2, pp. 327-35, (2014) (PubMed).

Bandeira-Melo, Weller, Bozza: "Identifying intracellular sites of eicosanoid lipid mediator synthesis with EicosaCell assays." in: Methods in molecular biology (Clifton, N.J.), Vol. 717, pp. 277-89, (2011) (PubMed).

Target Details for ADRP

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Alternative Name: ADRP

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism