Ectodysplasin A antibody (N-Term)
Quick Overview for Ectodysplasin A antibody (N-Term) (ABIN2840705)
Target
See all Ectodysplasin A (EDA) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 47-76, N-Term
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Predicted Reactivity
- B
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This EDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-76 amino acids from the N-terminal region of human EDA.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
- 6 months
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- Ectodysplasin A (EDA)
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Alternative Name
- EDA
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Background
- EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. This protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in the gene for EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.
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Molecular Weight
- 41294
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Gene ID
- 1896
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NCBI Accession
- NP_001005609, NP_001005610, NP_001005612, NP_001005613, NP_001390
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UniProt
- Q92838
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Pathways
- Tube Formation
Target
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