Haptoglobin antibody (Center)

Catalog No. ABIN2842566

This anti-Haptoglobin antibody is a Rabbit Polyclonal antibody detecting Haptoglobin in WB, FACS and IHC (p). Suitable for Human and Mouse.

Quick Overview for Haptoglobin antibody (Center) (ABIN2842566)

Target: Haptoglobin (HP)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Haptoglobin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB21463

Product Details anti-Haptoglobin Antibody

Binding Specificity: AA 295-322, Center

Specificity: This HP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301~331 amino acids from the Center region of human HP.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 AA from the Central region of human HP.

Isotype: Ig Fraction

Application Details

Application Notes: WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Haptoglobin

Target: Haptoglobin (HP)

Alternative Name: HP

Background: HP is a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia.
Synonyms: Haptoglobin beta chain, Haptoglobin alpha chain, Haptoglobin, HP

Molecular Weight: 45205 DA

Gene ID: 3240

UniProt: P00738

Pathways: Transition Metal Ion Homeostasis