Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
PBS, 0.09 % NaN3, 1 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store in the dark at 2-8 °C.
Target
Sema4a
(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a))
Alternative Name
SEMA4A
Background
Semaphorins are involved in guidance of axonal migration during neuronal development and in immune responses. Sema4A, a class IV semaphorin that was originally identified as SemB, is a transmembrane protein expressed by dendritic cells and B cells. Sema4A enhances the activation and differentiation of T cells and generation of antigen-specific T cells via interaction with its receptor, Tim-2.Synonyms: SEMAB, SEMB, Sema B, Semaphorin-4A, Semaphorin-B