ODC1 antibody

Catalog No. ABIN2854335

This anti-ODC1 antibody is a Rabbit Polyclonal antibody detecting ODC1 in WB and IHC (p). Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for ODC1 antibody (ABIN2854335)

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ODC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ODC1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit polyclonal antibody to ODC (ornithine decarboxylase 1)
ODC antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ODC. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.19 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-ODC1 antibody (ABIN2854335)

Sekiguchi, Seki, Kawai, Yoshida, Yoshida, Isobe, Hoshino, Shirai, Tanaka, Souzaki, Watanabe, Arakawa, Nannya, Suzuki, Fujii, Kataoka, Shiraishi, Chiba, Tanaka, Shimamura, Sato, Sato-Otsubo, Kimura et al.: "Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets. ..." in: NPJ precision oncology, Vol. 4, pp. 20, (2020) (PubMed).

Target Details for ODC1

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Alternative Name: ornithine decarboxylase 1

Background: This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.

Molecular Weight: 51 kDa

Gene ID: 4953

UniProt: P11926