Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

ADAR antibody

This anti-ADAR antibody is a Rabbit Polyclonal antibody detecting ADAR in WB, IF, IP, IHC (p) and ICC. Suitable for Human. This Primary Antibody has been cited in 1 publication.
Catalog No. ABIN2855100

Quick Overview for ADAR antibody (ABIN2855100)

Target

See all ADAR Antibodies
ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Reactivity

  • 85
  • 29
  • 24
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 81
  • 5
  • 1
Rabbit

Clonality

  • 73
  • 14
Polyclonal

Conjugate

  • 37
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This ADAR antibody is un-conjugated

Application

  • 57
  • 27
  • 27
  • 22
  • 21
  • 9
  • 9
  • 8
  • 7
  • 6
  • 3
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Grade

KO Validated
  • Cross-Reactivity

    Human, Rat

    Characteristics

    Rabbit Polyclonal antibody to ADAR1 (adenosine deaminase, RNA-specific)
    ADAR1 antibody [N3C1], Internal

    Purification

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human ADAR1. The exact sequence is proprietary.

    Isotype

    IgG
  • Application Notes

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Comment

    Positive Control: 293T , A431 , HeLa , HepG2

    Validation: KO/KD

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.82 mg/mL

    Buffer

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Stejskal, Rájecká, Covelo-Molares, Sinigaglia, Brožinová, Kašiarová, Dohnálková, Reyes-Gutierrez, Cahová, Keegan, O'Connell, Vaňáčová: "Global analysis by LC-MS/MS of N6-methyladenosine and inosine in mRNA reveal complex incidence." in: RNA (New York, N.Y.), Vol. 31, Issue 4, pp. 514-528, (2025) (PubMed).

  • Target

    ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

    Alternative Name

    adenosine deaminase RNA specific

    Background

    This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Cellular Localization: Cytoplasm , Nucleus , nucleolus

    Molecular Weight

    136 kDa

    Gene ID

    103

    UniProt

    P55265

    Pathways

    Protein targeting to Nucleus
You are here:
Chat with us!