SNRPB antibody

Catalog No. ABIN2855215

This Rabbit Polyclonal antibody specifically detects SNRPB in WB, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for SNRPB antibody (ABIN2855215)

Target: SNRPB (Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRPB antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-SNRPB Antibody

Cross-Reactivity: Drosophila melanogaster, Human

Characteristics: Rabbit Polyclonal antibody to SNRPB (small nuclear ribonucleoprotein polypeptides B and B1)
SNRPB antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SNRPB. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa nucleus

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.38 mg/mL

Buffer: 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SNRPB

Target: SNRPB (Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB))

Alternative Name: small nuclear ribonucleoprotein polypeptides B and B1

Background: The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.

Cellular Localization: Nucleus

Molecular Weight: 25 kDa

Gene ID: 6628

UniProt: P14678

Pathways: Ribonucleoprotein Complex Subunit Organization