RELT antibody (Center)

Catalog No. ABIN2855800

This Rabbit Polyclonal antibody specifically detects RELT in WB, IF, ICC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for RELT antibody (Center) (ABIN2855800)

Target: RELT (RELT Tumor Necrosis Factor Receptor (RELT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RELT antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RELT Antibody

Binding Specificity: Center

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Mouse (87 %), Rat (86 %)

Characteristics: Rabbit Polyclonal antibody to RELT (RELT tumor necrosis factor receptor)
RELT antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human RELT. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RELT

Target: RELT (RELT Tumor Necrosis Factor Receptor (RELT))

Alternative Name: RELT

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

Cellular Localization: Cell membrane, Single-pass type I membrane protein , Cytoplasm

Molecular Weight: 46 kDa

Gene ID: 84957