Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (Center) antibody

Details for Product No. ABIN2856042
Antigen
  • TAK1
  • TR2R1
  • TR4
  • hTAK1
  • Tr4
  • gb:dq017625
  • im:6911408
  • mKIAA4145
  • nuclear receptor subfamily 2 group C member 2
  • nuclear receptor subfamily 2, group C, member 2
  • NR2C2
  • Nr2c2
  • nr2c2
Epitope
Center
48
42
24
17
16
15
15
15
15
15
13
12
11
9
8
5
4
4
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
306
213
210
12
8
8
6
6
5
5
4
3
2
2
2
1
Host
Rabbit
280
30
1
Clonality
Polyclonal
Conjugate
Un-conjugated
17
14
14
14
14
14
14
9
9
6
6
6
6
6
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
196
79
79
73
42
8
4
2
2
1
1
1
Options
Immunogen Recombinant protein encompassing a sequence within the center region of human NR2C2. The exact sequence is proprietary.
Isotype IgG
Cross-Reactivity Mouse (Murine), Rat (Rattus), Cow (Bovine)
Cross-Reactivity (Details) Mouse (97 %), Rat (97 %), Bovine (96 %)
Characteristics Rabbit Polyclonal antibody to NR2C2 (nuclear receptor subfamily 2, group C, member 2)
NR2C2 antibody
Purification Purified by antigen-affinity chromatography.
Antigen
Alternative Name NR2C2 (NR2C2 Antibody Abstract)
Background Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).[supplied by OMIM]

Cellular Localization: Nucleus
Molecular Weight 65 kDa
Gene ID 7182
Pathways TCR Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades
Application Notes Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
Comment

Positive Control: H1299 , Molt-4

Restrictions For Research Use only
Format Liquid
Concentration 0.42 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (Center) antibody (ABIN2856042) ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NR2C2,...
Image no. 2 for anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (Center) antibody (ABIN2856042) IHC-P Image Immunohistochemical analysis of paraffin-embedded NCIN87 Xenograft, using...
Image no. 3 for anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (Center) antibody (ABIN2856042) WB Image Sample (30μg whole cell lysate) A:H1299 B:MOLT4 , 7.5% SDS PAGE antibody dil...
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