GNAT1 antibody (Center)

Catalog No. ABIN2856227

The Rabbit Polyclonal anti-GNAT1 antibody has been validated for WB. It is suitable to detect GNAT1 in samples from Human.

Quick Overview for GNAT1 antibody (Center) (ABIN2856227)

Target: GNAT1 (Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNAT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GNAT1 Antibody

Binding Specificity: Center

Cross-Reactivity: Dog (Canine)

Cross-Reactivity (Details): Dog (100 %)

Characteristics: Rabbit Polyclonal antibody to GNAT1 (guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1)
GNAT1 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GNAT1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: NT2D1 , IMR32 , U87-MG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GNAT1

Target: GNAT1 (Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1))

Alternative Name: GNAT1

Background: Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molecular Weight: 40 kDa

Gene ID: 2779

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Phototransduction