DPY19L4 antibody (C-Term)

Catalog No. ABIN2856454

This Rabbit Polyclonal antibody specifically detects DPY19L4 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for DPY19L4 antibody (C-Term) (ABIN2856454)

Target: DPY19L4 (Dpy-19-Like 4 (DPY19L4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPY19L4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DPY19L4 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Mouse (94 %)

Characteristics: Rabbit Polyclonal antibody to DPY19L4 (dpy-19-like 4 (C. elegans))
DPY19L4 antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human DPY19L4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: A549 , HeLa , HepG2 , HCT116

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DPY19L4

Target: DPY19L4 (Dpy-19-Like 4 (DPY19L4))

Alternative Name: DPY19L4

Background: Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Cellular Localization: Membrane

Molecular Weight: 84 kDa

Gene ID: 286148