UFD1L antibody (full length)

Catalog No. ABIN2856688

This Rabbit Polyclonal antibody specifically detects UFD1L in WB, IF, IHC (p) and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for UFD1L antibody (full length) (ABIN2856688)

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UFD1L antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-UFD1L Antibody

Binding Specificity: full length

Cross-Reactivity: Rhesus Monkey

Cross-Reactivity (Details): Rhesus Monkey (100 %)

Characteristics: Rabbit Polyclonal antibody to UFD1L (ubiquitin fusion degradation 1 like (yeast))
UFD1L antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human UFD1L Recombinant protein.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:5000-1:20000*

Comment:

Positive Control: A431 , H1299 , mouse lung

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.02 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for UFD1L

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Alternative Name: UFD1L

Background: The protein encoded by this gene forms a complex with two other proteins, NPL4 and VCP, that is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms.

Cellular Localization: Nucleus (By similarity) , Cytoplasm , cytosol

Molecular Weight: 35 kDa

Gene ID: 7353