Ugt1 antibody

Catalog No. ABIN2856950

The Rabbit Polyclonal anti-Ugt1 antibody has been validated for WB and IHC (p). It is suitable to detect Ugt1 in samples from Human. There are 3+ publications available.

Quick Overview for Ugt1 antibody (ABIN2856950)

Target: Ugt1 (UGT1A) (UDP Glucuronosyltransferase 1 Family, Polypeptide A Complex Locus (UGT1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ugt1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Ugt1 Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to UGT1A (UDP glucuronosyltransferase 1 family, polypeptide A)
UGT1A antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human UGT1A. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse liver , 293T , A431 , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.47 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-Ugt1 antibody (ABIN2856950)

Langhans, Strassburg, Röcken, Kalthoff: "A Common UDP-Glucuronosyltransferase (UGT)1A Haplotype Is Associated With Accelerated Aging in Humanized Transgenic Mice." in: Oxidative medicine and cellular longevity, Vol. 2025, pp. 3203439, (2025) (PubMed).

Landerer, Kalthoff, Paulusch, Strassburg: "UDP-glucuronosyltransferase polymorphisms affect diethylnitrosamine-induced carcinogenesis in humanized transgenic mice." in: Cancer science, Vol. 111, Issue 11, pp. 4266-4275, (2020) (PubMed).

Zahreddine, Culjkovic-Kraljacic, Gasiorek, Duchaine, Borden: "GLI1-Inducible Glucuronidation Targets a Broad Spectrum of Drugs." in: ACS chemical biology, Vol. 14, Issue 3, pp. 348-355, (2019) (PubMed).

Target Details for Ugt1

Target: Ugt1 (UGT1A) (UDP Glucuronosyltransferase 1 Family, Polypeptide A Complex Locus (UGT1A))

Alternative Name: UGT1A

Gene ID: 54600