Cadherin 5 antibody (AA 1-258)

Catalog No. ABIN285709

This Rabbit Polyclonal antibody specifically detects Cadherin 5 in WB, ELISA, FACS and IHC (fro). It exhibits reactivity toward Cow.

Quick Overview for Cadherin 5 antibody (AA 1-258) (ABIN285709)

Target: Cadherin 5 (CDH5)

Reactivity: Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Cadherin 5 Antibody

Binding Specificity: AA 1-258

Cross-Reactivity: Cow (Bovine), Mouse (Murine), Rat (Rattus)

Purification: Purified

Immunogen: CD144 antibody was raised in rabbit using recombinant protein fragments corresponding to amino acids 1-258 of VE-cadherin as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified IgG supplied in PBS.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: CD144

Background: VE-Cadherin is a 120 kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cellcontacts, called adherens junctions.

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2