ICC: 1:100-1:400, IHC: 1:2,000, IP: 1-10 µL, WB: 1:500-1:2,000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
Lot specific
Buffer
Neat rabbit antiserum, with 0.02 % NaN3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
-20 °C
Storage Comment
Aliquot and store at -20 °C.
Target
GAP43
(Growth Associated Protein 43 (GAP43))
Alternative Name
GAP43
Background
GAP-43, a common marker of differentiating neurons, is expressed at elevated levels by developing or regenerating neurons during axon growth. While GAP-43 is an integral membrane protein associated with the cytoplasmic surface of axonal growth cones (and synapses), it is absent from dendritic growth cones. In adult brain, GAP-43 is found in highconcentration in presynaptic areas where memory formation is thought to occur, such asfrontal cortex, limbic system and hippocampus.