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Botulinum Neurotoxin Type A antibody

The Rabbit Polyclonal anti-Botulinum Neurotoxin Type A antibody has been validated for WB and EIA. It is suitable to detect Botulinum Neurotoxin Type A in samples from Clostridium botulinum.
Catalog No. ABIN2859514

Quick Overview for Botulinum Neurotoxin Type A antibody (ABIN2859514)

Target

Botulinum Neurotoxin Type A

Reactivity

  • 21
  • 1
Clostridium botulinum

Host

  • 11
  • 7
  • 3
  • 1
Rabbit

Clonality

  • 11
  • 11
Polyclonal

Conjugate

  • 18
  • 2
  • 1
  • 1
This Botulinum Neurotoxin Type A antibody is un-conjugated

Application

  • 16
  • 13
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Purification

    Protein G Sepharose Chromatography.

    Immunogen

    Type A Neurotoxin and Complexing Proteins Toxoid.
  • Application Notes

    Suitable for use in Dot blot, ELISA (1/10,000) and Western blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.5 mg/mL (OD280nm, E0.1%=1.4)

    Buffer

    1x PBS, pH 7.2 containing 20 % Glycerol and no preservative.

    Preservative

    Without preservative

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    -20 °C
  • Target

    Botulinum Neurotoxin Type A

    Background

    Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.Synonyms: BOTOX, BoNT/A, Bontoxilysin-A, Clostridium botulinum Toxin A

    Gene ID

    1491

    UniProt

    P10845
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