The Rabbit Polyclonal anti-Botulinum Neurotoxin Type A antibody has been validated for WB and EIA. It is suitable to detect Botulinum Neurotoxin Type A in samples from Clostridium botulinum.
Catalog No. ABIN2859514
Quick Overview for Botulinum Neurotoxin Type A antibody (ABIN2859514)
Target
Botulinum Neurotoxin Type A
Reactivity
Clostridium botulinum
Host
Rabbit
Clonality
Polyclonal
Conjugate
This Botulinum Neurotoxin Type A antibody is un-conjugated
Reactivity: Clostridium botulinum
ELISA, WB, DB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Suitable for use in Dot blot, ELISA (1/10,000) and Western blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.5 mg/mL (OD280nm, E0.1%=1.4)
Buffer
1x PBS, pH 7.2 containing 20 % Glycerol and no preservative.
Preservative
Without preservative
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Target
Botulinum Neurotoxin Type A
Background
Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.Synonyms: BOTOX, BoNT/A, Bontoxilysin-A, Clostridium botulinum Toxin A