CXCL12 antibody (AA 20-89)

Catalog No. ABIN285962

The Rabbit Polyclonal anti-CXCL12 antibody has been validated for WB and ICC. It is suitable to detect CXCL12 in samples from Mouse.

Quick Overview for CXCL12 antibody (AA 20-89) (ABIN285962)

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL12 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Product Details anti-CXCL12 Antibody

Binding Specificity: AA 20-89

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Purification: purified

Immunogen: SDF1 a antibody was raised in rabbit using E. Coli-expressed amino acids 20-89 of murine SDF-1 alpha as the immunogen.

Isotype: IgG

Application Details

Application Notes: ICC, 1:100, WB: 1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitue in distilled water.

Concentration: Lot specific

Buffer: Supplied as a lyophilized Potein A purified rabbit IgG with 0.1 % NaN3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20 °C for short term storage, -70 °C for long-term storage.

Target Details for CXCL12

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Alternative Name: SDF1 alpha

Background: SDF-1 (stromal cell-derived factor-1) is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1.

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling