PGE2 antibody

Catalog No. ABIN2869135

This anti-PGE2 antibody is a Mouse Monoclonal antibody detecting PGE2 in IA. Suitable for Human.

Quick Overview for PGE2 antibody (ABIN2869135)

Target: PGE2 (Prostaglandin E2 (PGE2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PGE2 antibody is un-conjugated

Application: Immunoassay (IA)

Clone: 5A2

Product Details anti-PGE2 Antibody

Immunogen: PGE2 covalently coupled to carrier protein

Application Details

Application Notes: For Immunoassay Use

Comment:

Mouse Monoclonal to Prostaglandin E2 (PGE2) Extend primary antibody supplies Clone 5A2

Restrictions: For Research Use only

Handling

Buffer: 100 mM Sodium Phosphate, 150 mM Sodium Chloride, 0.09 % Na Azide, pH 7.2

Target Details for PGE2

Target: PGE2 (Prostaglandin E2 (PGE2))

Alternative Name: Prostaglandin E2

Background: Eicosanoid signal transduction pathways are highly conserved and are involved in a number of physiological processes. Prostaglandins are synthesized from arachidonic acid by cyclooxygenase (COX)-1 or -2, which con- vert the acid into PGH2. This is further processed by cytosolic or microsomal prostaglandin synthases to become PGE2 or one of several other prostanoids. Prostacyclin is the major cyclooxygenase product in blood vessel walls and it is present in inflammatory fluids in similar concentrations to PGE2. Prostacyclin is a potent vasodilator and is more potent than PGE2 in producing hyperalgesia. PGE2 is produced by a wide variety of tissues and in several pathological conditions, including inflammation, arthritis, fever, tissue injury, endometriosis, and a variety of cancers. Other biological actions of PGE2 include vasodilation, modulation of sleep/wake cycles, and facilitation of human immunodeficiency virus replication. It elevates cAMP levels, stimulates bone resorption, and has thermoregula- tory effects. It has been shown to be a regulator of sodium excretion and renal hemodynamics.