mGluR1 alpha antibody (Internal Region)

Catalog No. ABIN289441

This Rabbit Polyclonal antibody specifically detects mGluR1 alpha in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for mGluR1 alpha antibody (Internal Region) (ABIN289441)

Target: mGluR1 alpha (mGluR1a) (Glutamate Receptor, Metabotropic 1 alpha (mGluR1a))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This mGluR1 alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-mGluR1 alpha Antibody

Binding Specificity: Internal Region

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Purification: Affinity chromatography purified

Immunogen: mGluR1 alpha antibody was raised in rabbit using a synthetic peptide comprising internal residues of the human GluR1 alpha protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: IHC: 1:100-1:500, WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified and supplied in PBS, with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for mGluR1 alpha

Target: mGluR1 alpha (mGluR1a) (Glutamate Receptor, Metabotropic 1 alpha (mGluR1a))

Alternative Name: mGluR1 alpha

Background: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups. The Glutamate Receptor, Metabotropic, 1, (mGluR1 alpha) activates phospholipase C and participates in the central action of glutamate in the central nervous system, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.