ATM, ATR Substrate Motif (pSer), (pThr) antibody
Quick Overview for ATM, ATR Substrate Motif (pSer), (pThr) antibody (ABIN290459)
Target
Reactivity
Host
Clonality
Application
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Binding Specificity
- pSer, pThr
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Specificity
- Detects endogenous levels of proteins containing the phospho-(Ser/Thr) ATM/ATR substrate motif. Preferentially binds peptides/proteins that contain phospho-Ser/Thr preceded by Leu or similar hydrophobic amino acids at the -1 position and followed by Gln at the +1 position. No cross-reactivity is observed with corresponding non-phosphorylated sequences or with other phospho-Ser/Thr-containing motifs. Species cross-reactivity: All species.
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Purification
- Immunoaffinity Chromatography
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Immunogen
- Synthetic phospho-(Ser/Thr) ATM/ATR substrate peptides.
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Isotype
- IgG
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Application Notes
- ELISA (1:1000), ICC, IHC-P, IP (1:20), WB (1:1000)
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50% glycerol.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.
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- ATM, ATR Substrate Motif
Target
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