beta Amyloid 1-16 antibody

Catalog No. ABIN2961825

This Mouse Monoclonal antibody specifically detects in WB, IF, IP, IHC and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for beta Amyloid 1-16 antibody (ABIN2961825)

Target: beta Amyloid 1-16

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA

Clone: Ab3

Product Details

Specificity: Reacts with humanand mouse Aβ1-16 as well as other Aβ peptides: Aβ37, Aβ38, Aβ39, Aβ40 and Aβ42

Purification: Purified

Immunogen: Synthetic peptide corresponding to Abeta1-16.

Isotype: IgG1

Application Details

Application Notes: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
1 - 10 μg/mL for any applications

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4.

Handling Advice: Dilute in PBS or medium which is identical to that used in the assay system.

Storage: -20 °C

Storage Comment: Stable for at least one year at -20°C

Expiry Date: 12 months

Target Details

Target: beta Amyloid 1-16

Alternative Name: Amyloid beta 1-16

Background: Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). There is now compelling evidence that metal binding to Aβ is involved in AD pathogenesis. The amino acid region 1-16 is widely considered as the metal binding domain of Aβ. Unlike copper(II) that prefers the N-terminal amino group as the main binding site, zinc(II) is preferentially placed in the 8-16 amino acidic region of Aβ (1-16).

Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Gene name: APP, A4, AD1

Gene ID: 351

UniProt: P05067