LACTB antibody

Catalog No. ABIN2962025

This anti-LACTB antibody is a Mouse Monoclonal antibody detecting LACTB in ELISA. Suitable for Enterobacter cloacae.

Quick Overview for LACTB antibody (ABIN2962025)

Target: LACTB (Lactamase, beta (LACTB))

Reactivity: Enterobacter cloacae

Host: Mouse

Clonality: Monoclonal

Conjugate: This LACTB antibody is un-conjugated

Application: ELISA

Clone: 3E11-G3

Product Details anti-LACTB Antibody

Specificity: Reacts withType IV betalactamase of Enterobacter cloacae.

Purification: Purified

Immunogen: Type IV beta lactamase from Enterobacter cloacae, accession no. P05364.

Isotype: IgG3

Application Details

Application Notes: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
ELISA10 - 20 μg/mL (optimized for beta-lactamase on solid phase at 10 μg/mL).

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4

Handling Advice: Dilute in PBS or medium that is identical to that used in the assay system.

Storage: -20 °C

Storage Comment: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LACTB

Target: LACTB (Lactamase, beta (LACTB))

Alternative Name: beta-Lactamase

Background: The beta-lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta-lactams are structurally related through the presence of a core beta-lactam ring. Bacterial resistance to beta-lactams continues to increase, primarily due to microbial production of beta-lactamases. Beta-lactamases catalyze the hydrolysis of the beta-lactam bond which destroys anti-bacterial activity. Bacteria the produce TEM- or SHV-type beta-lactamases have point mutations in structural genes that have extended the substrate specificity of these betalactamases. As a result, many of the beta-lactamase-producing Gram-negative bacteria have become multi-drug resistant. Beta-lactamase from Enterobacter cloacae is a serine beta-lactamase with substrate specificity for cephalosporins.

Beta-lactamase Cephalosporinase Gene nam: ampC E. cloacae

UniProt: P05364