Cadherin 5 antibody (AA 259-358)

Catalog No. ABIN3015299

This anti-Cadherin 5 antibody is a Rabbit Polyclonal antibody detecting Cadherin 5 in WB. Suitable for Human.

Quick Overview for Cadherin 5 antibody (AA 259-358) (ABIN3015299)

Target: Cadherin 5 (CDH5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cadherin 5 Antibody

Binding Specificity: AA 259-358

Sequence: TQTKYTFVVP EDTRVGTSVG SLFVEDPDEP QNRMTKYSIL RGDYQDAFTI ETNPAHNEGI IKPMKPLDYE YIQQYSFIVE ATDPTIDLRY MSPPAGNRAQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 259-358 of human VE Cadherin (NP_001786.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: CDH5

Background: This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.,CDH5,7B4,CD144,cadherin-5,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cell Adhesion Molecules,Tight Junctions,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Cardiovascular,Cardiovascular Markers,Endothelial Cells,CDH5

Molecular Weight: 74 kDa/87 kDa

Gene ID: 1003

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2