Prostacyclin Receptor antibody (AA 207-386)

Catalog No. ABIN3015619

Product Details anti-Prostacyclin Receptor Antibody

Target: Prostacyclin Receptor (PTGIR)

Binding Specificity: AA 207-386

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prostacyclin Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TLSLCRMYRQ QKRHQGSLGP RPRTGEDEVD HLILLALMTV VMAVCSLPLT IRCFTQAVAP DSSSEMGDLL AFRFYAFNPI LDPWVFILFR KAVFQRLKLW VCCLCLGPAH GDSQTPLSQL ASGRRDPRAP SAPVGKEGSC VPLSAWGEGQ VEPLPPTQQS SGSAVGTSSK AEASVACSLC

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 207-386 of human PTGIR (NP_000951.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Prostacyclin Receptor

Target: Prostacyclin Receptor (PTGIR)

Alternative Name: PTGIR (PTGIR Products)

Synonyms: IP antibody, PGI2 antibody, PRIPR antibody, prostaglandin I receptor (IP) antibody, prostaglandin I2 receptor antibody, Ptgir antibody, PTGIR antibody

Background: The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.,PTGIR,IP,PRIPR,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cardiovascular,PTGIR

Molecular Weight: 40 kDa

Gene ID: 5739

UniProt: P43119

Pathways: cAMP Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling