Prostacyclin Receptor antibody
Quick Overview for Prostacyclin Receptor antibody (ABIN1944827)
Target
See all Prostacyclin Receptor (PTGIR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Isotype
- IgG1
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Application Notes
- IF: 1:100. WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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Storage
- 4 °C,-20 °C
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: "Structural organization and chromosomal assignment of the human prostacyclin receptor gene." in: Genomics, Vol. 27, Issue 1, pp. 142-8, (1995) (PubMed).
: "Cloning and expression of a cDNA for the human prostanoid IP receptor." in: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 12173-8, (1994) (PubMed).
: "Cloning and expression of a cDNA for the human prostacyclin receptor." in: FEBS letters, Vol. 344, Issue 1, pp. 74-8, (1994) (PubMed).
: "Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system." in: Circulation, Vol. 90, Issue 4, pp. 1643-7, (1994) (PubMed).
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- Prostacyclin Receptor (PTGIR)
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Alternative Name
- Prostacyclin Receptor
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Background
- Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
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Molecular Weight
- 40956 Da
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Gene ID
- 5739
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UniProt
- P43119
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Pathways
- cAMP Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling
Target
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