Ezrin antibody (pThr567)
Quick Overview for Ezrin antibody (pThr567) (ABIN3019809)
Target
See all Ezrin (EZR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pThr567
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Phosphorylated Antibodies
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Purification
- Affinity purification
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Immunogen
- A phospho specific peptide corresponding to residues surrounding T567 of human Ezrin
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Ezrin (EZR)
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Alternative Name
- EZR
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Background
- The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.,CVIL,CVL,HEL-S-105,VIL2,EZR,Ezrin,ezrin,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Protein phosphorylation,EZR
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Molecular Weight
- 69 kDa
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Gene ID
- 7430
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UniProt
- P15311
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Pathways
- Maintenance of Protein Location
Target
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