DOK2 antibody (pTyr299)

Catalog No. ABIN3019935

This Rabbit Polyclonal antibody specifically detects DOK2 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for DOK2 antibody (pTyr299) (ABIN3019935)

Target: DOK2

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-DOK2 Antibody

Binding Specificity: pTyr299

Cross-Reactivity: Human

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding Y299 of human DOK2

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:100 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DOK2

Target: DOK2

Alternative Name: DOK2

Background: The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.,DOK2,p56DOK,p56dok-2,Cancer,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,Protein phosphorylation,DOK2

Molecular Weight: 45 kDa

Gene ID: 9046

UniProt: O60496