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EIF2S1 antibody (pSer49)

EIF2S1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3020187
  • Target See all EIF2S1 Antibodies
    EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
    Binding Specificity
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer49
    Reactivity
    • 68
    • 33
    • 28
    • 10
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 55
    • 13
    • 2
    Rabbit
    Clonality
    • 53
    • 17
    Polyclonal
    Conjugate
    • 55
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF2S1 antibody is un-conjugated
    Application
    • 56
    • 35
    • 25
    • 25
    • 12
    • 10
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Phosphorylated Antibodies
    Purification
    Affinity purification
    Immunogen
    A phospho specific peptide corresponding to residues surrounding S49 of human EIF2S1
    Isotype
    IgG
    Top Product
    Discover our top product EIF2S1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:100 - 1:200
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
    Alternative Name
    EIF2S1 (EIF2S1 Products)
    Background
    The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2, MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],EIF-2,EIF-2A,EIF-2alpha,EIF2,EIF2A,EIF2S1,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,Regulation of eIF2,Cell Biology & Developmental Biology,Protein folding,Protein phosphorylation,EIF2S1
    Molecular Weight
    36 kDa
    Gene ID
    1965
    UniProt
    P05198
    Pathways
    Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C
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