Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CRADD antibody (AA 1-199)

CRADD Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3021483
  • Target See all CRADD Antibodies
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    Binding Specificity
    • 15
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-199
    Reactivity
    • 45
    • 4
    • 2
    Human
    Host
    • 39
    • 6
    • 1
    • 1
    Rabbit
    Clonality
    • 38
    • 9
    Polyclonal
    Conjugate
    • 27
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRADD antibody is un-conjugated
    Application
    • 36
    • 22
    • 10
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLLLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human RAIDD/RAIDD/CRADD (NP_003796.1).
    Isotype
    IgG
    Top Product
    Discover our top product CRADD Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    Alternative Name
    CRADD (CRADD Products)
    Background
    This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.,CRADD,MRT34,RAIDD,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Death Receptor Signaling Pathway,CRADD
    Molecular Weight
    11 kDa/22 kDa
    Gene ID
    8738
    UniProt
    P78560
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
You are here:
Support