CRADD antibody (AA 69-98)

Catalog No. ABIN1538574

Product Details anti-CRADD Antibody

Target: CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))

Binding Specificity: AA 69-98

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRADD antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CRADD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the Central region of human CRADD.

Clone: RB39320

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CRADD Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for CRADD

Target: CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))

Alternative Name: CRADD (CRADD Products)

Synonyms: cradd antibody, MGC89035 antibody, zgc:101717 antibody, CRADD antibody, DKFZp468A2219 antibody, LOC100226369 antibody, raidd antibody, MGC78788 antibody, MRT34 antibody, RAIDD antibody, CASP2 and RIPK1 domain containing adaptor with death domain antibody, CASP2 and RIPK1 domain containing adaptor with death, gene 1 antibody, CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog antibody, CRADD antibody, cradd.1 antibody, cradd antibody, cradd.2.S antibody, Cradd antibody

Background: The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.

Molecular Weight: 22745

Gene ID: 8738

NCBI Accession: NP_003796

UniProt: P78560

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity