Dystonin antibody (AA 1-270)

Catalog No. ABIN3022723

The Rabbit Polyclonal anti-Dystonin antibody has been validated for WB and IHC. It is suitable to detect Dystonin in samples from Human.

Quick Overview for Dystonin antibody (AA 1-270) (ABIN3022723)

Target: Dystonin (DST)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dystonin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Dystonin Antibody

Binding Specificity: AA 1-270

Sequence: MHSSSYSYRS SDSVFSNTTS TRTSLDSNEN LLLVHCGPTL INSCISFGSE SFDGHRLEML QQIANRVQRD SVICEDKLIL AGNALQSDSK RLESGVQFQN EAEIAGYILE CENLLRQHVI DVQILIDGKY YQADQLVQRV AKLRDEIMAL RNECSSVYSK GRILTTEQTK LMISGITQSL NSGFAQTLHP SLTSGLTQSL TPSLTSSSMT SGLSSGMTSR LTPSVTPAYT PGFPSGLVPN FSSGVEPNSL QTLKLMQIRK PLLKSSLLDQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human DST (NP_001714.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Dystonin

Target: Dystonin (DST)

Alternative Name: DST

Background: This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been reported that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.,DST,BP240,BPA,BPAG1,CATX-15,CATX15,D6S1101,DMH,DT,EBSB2,HSAN6,MACF2,dystonin,DST

Molecular Weight: 9 kDa/25 kDa/50 kDa/102 kDa/306-860 kDa

Gene ID: 667

UniProt: Q03001