TGFBI antibody (AA 481-683)

Catalog No. ABIN3023373

Product Details anti-TGFBI Antibody

Target: TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))

Binding Specificity: AA 481-683

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFBI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: AHDKRGRYGT LFTMDRVLTP PMGTVMDVLK GDNRFSMLVA AIQSAGLTET LNREGVYTVF APTNEAFRAL PPRERSRLLG DAKELANILK YHIGDEILVS GGIGALVRLK SLQGDKLEVS LKNNVVSVNK EPVAEPDIMA TNGVVHVITN VLQPPANRPQ ERGDELADSA LEIFKQASAF SRASQRSVRL APVYQKLLER MKH

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 481-683 of human TGF beta induced TGF beta induced TGFBI (NP_000349.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-TGFBI antibody (ABIN3023373)

Wang, Hu, Zhou, Xiong, Zhang, Shehada, Hu, Song, Chen: "Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling." in: Scientific reports, Vol. 7, Issue 1, pp. 13321, (2017) (PubMed).

Target Details for TGFBI

Target: TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))

Alternative Name: TGFBI (TGFBI Products)

Background: This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.,TGFBI,BIGH3,CDB1,CDG2,CDGG1,CSD,CSD1,CSD2,CSD3,EBMD,LCD1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,Bone,Growth factor,Neuroscience,TGFBI

Molecular Weight: 74 kDa

Gene ID: 7045

UniProt: Q15582