TGFBI antibody

Catalog No. ABIN7245623

Product Details anti-TGFBI Antibody

Target: TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFBI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human TGFBI

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.02 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TGFBI

Target: TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))

Alternative Name: TGFBI (TGFBI Products)

Synonyms: TGFBI antibody, BIGH3 antibody, CDB1 antibody, CDG2 antibody, CDGG1 antibody, CSD antibody, CSD1 antibody, CSD2 antibody, CSD3 antibody, EBMD antibody, LCD1 antibody, 68kDa antibody, AI181842 antibody, AI747162 antibody, Beta-ig antibody, big-h3 antibody, Big-h3 antibody, MP70 antibody, MP78 antibody, hm:zeh0933 antibody, wu:fa13f05 antibody, zgc:110495 antibody, transforming growth factor beta induced antibody, transforming growth factor, beta induced antibody, transforming growth factor, beta-induced antibody, TGFBI antibody, Tgfbi antibody, tgfbi antibody

Background: TGFBI,also named as BIGH3,Kerato-epithelin and RGD-CAP,binds to type I,II,and IV collagens. TGFBI is an adhesion protein which may play an important role in cell-collagen interactions. In cartilage,it may be involved in endochondral bone formation. TGFBI is an extracellular matrix adaptor protein,it has been reported to be differentially expressed in transformed tissues. TGFBI is a predictive factor of the response to chemotherapy,and suggest the use of TGFBI-derived peptides as possible therapeutic adjuvants for the enhancement of responses to chemotherapy. Defects in TGFBI are the cause of epithelial basement membrane corneal dystrophy (EBMD). Defects in TGFBI are the cause of corneal dystrophy Groenouw type 1 (CDGG1). Defects in TGFBI are the cause of corneal dystrophy lattice type 1 (CDL1). Defects in TGFBI are a cause of corneal dystrophy Thiel-Behnke type (CDTB). Defects in TGFBI are the cause of Reis-Buecklers corneal dystrophy (CDRB). Defects in TGFBI are the cause of lattice corneal dystrophy type 3A (CDL3A). Defects in TGFBI are the cause of Avellino corneal dystrophy (ACD).

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 75 kDa

UniProt: Q15582