FOXM1 antibody (AA 1-350)

Catalog No. ABIN3023679

This anti-FOXM1 antibody is a Rabbit Polyclonal antibody detecting FOXM1 in WB and ChIP. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for FOXM1 antibody (AA 1-350) (ABIN3023679)

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXM1 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Product Details anti-FOXM1 Antibody

Binding Specificity: AA 1-350

Sequence: MKTSPRRPLI LKRRRLPLPV QNAPSETSEE EPKRSPAQQE SNQAEASKEV AESNSCKFPA GIKIINHPTM PNTQVVAIPN NANIHSIITA LTAKGKESGS SGPNKFILIS CGGAPTQPPG LRPQTQTSYD AKRTEVTLET LGPKPAARDV NLPRPPGALC EQKRETCADG EAAGCTINNS LSNIQWLRKM SSDGLGSRSI KQEMEEKENC HLEQRQVKVE EPSRPSASWQ NSVSERPPYS YMAMIQFAIN STERKRMTLK DIYTWIEDHF PYFKHIAKPG WKNSIRHNLS LHDMFVRETS ANGKVSFWTI HPSANRYLTL DQVFKQQKRP NPELRRNMTI KTELPLGARR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human FOXM1 (NP_973732.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,ChIP,1:20 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-FOXM1 antibody (ABIN3023679)

Li, Sun, Li, Lv, Semukunzi, Li, Yu, Yuan, Lin: "DT-13 synergistically enhanced vinorelbine-mediated mitotic arrest through inhibition of FOXM1-BICD2 axis in non-small-cell lung cancer cells." in: Cell death & disease, Vol. 8, Issue 5, pp. e2810, (2018) (PubMed).

Jiang, Liao, He, Xin, Tu, Kong, Cui, Wang, Quan, Li, Zhang, Wang: "FoxM1 Directs STAT3 Expression Essential for Human Endometrial Stromal Decidualization." in: Scientific reports, Vol. 5, pp. 13735, (2016) (PubMed).

Target Details for FOXM1

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Alternative Name: FOXM1

Background: The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene.,FKHL16,FOXM1B,HFH-11,HFH11,HNF-3,INS-1,MPHOSPH2,MPP-2,MPP2,PIG29,TRIDENT,FOXM1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,FOXM1

Molecular Weight: 82 kDa/84 kDa/88 kDa

Gene ID: 2305

UniProt: Q08050

Pathways: Positive Regulation of Response to DNA Damage Stimulus