CD6 antibody

Catalog No. ABIN3024446

This Mouse Monoclonal antibody specifically detects CD6 in FACS, WB and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for CD6 antibody (ABIN3024446)

Target: CD6

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD6 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)

Clone: SPV-L14

Product Details anti-CD6 Antibody

Purification: Protein G affinity chromatography

Immunogen: A CD8+ cytotoxic T-cell clone was used as the immunogen for the CD6 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the CD6 antibody should be determined by the researcher.\. Western blot: 1-2 μg/mL, Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CD6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for CD6

Target: CD6

Alternative Name: CD6

Background: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular "scavenger receptor cysteine-rich" (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.