Recombinant MLANA antibody

Catalog No. ABIN3025217

This Rabbit Monoclonal antibody specifically detects MLANA in IF, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant MLANA antibody (ABIN3025217)

Target: MLANA (Melan A (MLANA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MLANA antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RMMRT1-1

Product Details anti-MLANA Antibody

Purification: Protein A affinity chromatography

Immunogen: Recombinant human protein was used as the immunogen for this MART-1 antibody.

Isotype: IgG kappa

Application Details

Application Notes: The optimal dilution of the MART-1 antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10  mM Citrate Buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.\. FACS: 0.5-1 μg/10^6 cells, Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the MART-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for MLANA

Target: MLANA (Melan A (MLANA))

Alternative Name: MART-1

Background: MART-1/Melan-A is a protein antigen that is found on the surface of melanocytes. Antibodies against the antigen are used in the medical specialty of anatomic pathology in order to recognize cells of melanocytic differentiation, useful for the diagnosis of a melanoma. The MART-1/Melan-A antigen is specific for the melanocyte lineage, found in normal skin, the retina, and melanocytes, but not in other normal tissues. It is thus useful as a marker for melanocytic tumors (melanomas) with the caveat that it is normally found in benign nevi as well. [Wiki]