PACRG antibody
Quick Overview for PACRG antibody (ABIN302748)
Target
See all PACRG AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- This antibody reacts to amino acids 204-215 of PACRG protein.
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Purification
- Immunoaffinity Chromatography
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Immunogen
- Synthetic peptide
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Application Notes
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Immunofluorescence. Western Blot: 1: 500 - 1: 3000. Immunohistochemistry: 1: 5 & 2.5 μg/mL. ELISA: 1: 2000 - 1: 10000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.2 mg/mL
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Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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- PACRG (PARK2 Co-Regulated (PACRG))
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Alternative Name
- PACRG
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Background
- PACRG (also known as Parkin coregulated gene protein and PARK2 coregulated) is a gene located very close to parkin, in reverse orientation on the chromosome. It is thought to be co-transcribed with parkin by a bi-directional promoter between the two genes. PACRG is expressed in all immune tissues, spleen, lymph nodes, thymus, tonsils, leukocyte and bone marrow and is also expressed in heart, brain, skeletal muscle, kidney, lung and pancreas. PACRG is expressed in primary Schwann cells and very weakly by monocyte-derived macrophages, which are the primary host cells of Mycobacterium leprae, the causative agent of leprosy. Splice variants have been described for this protein.Synonyms: GLUP, Molecular chaperone/chaperonin-binding protein, PARK2 coregulated gene protein, PARK2CRG, Parkin coregulated gene protein
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Gene ID
- 135138
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NCBI Accession
- NP_001073847
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UniProt
- Q96M98
Target
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