HIF1A
Reactivity: Human, Mouse, Rat, Cow, Dog
WB, IHC, IP, IF, ICC
Host: Mouse
Monoclonal
ESEE122
unconjugated
Application Notes
Titration of the HIF-1-alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
-20 °C
Storage Comment
The lyophilized HIF-1-alpha antibody can be stored at 4°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Hypoxia-inducible factor 1a (HIF-1-alpha) is a transcription factor that mediates cellular and systemic homeostatic responses to reduced O2 availability in mammals, including angiogenesis, erythropoiesis and glycolysis. It is crucial for the cellular response to hypoxia and plays a pivotal role in cellular adaptation to changes in oxygen availability.