Bcl-X/s (AA 120-130) antibody
Reactivity: Human, Mouse, Rat
WB, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
-
- Target
- Bcl-X/s
- Binding Specificity
- AA 120-130
- Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- Un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity
- Immunogen
- Amino acids 120-130 (YQSFEQDTFVE-human) were used as the immunogen for this Bcl-XS antibody.
- Isotype
- IgG
-
-
- Application Notes
- The stated application concentrations are suggested starting points. Titration of the Bcl-XS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Restrictions
- For Research Use only
-
- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Storage
- -20 °C
- Storage Comment
- After reconstitution, the Bcl-XS antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
- Target
- Bcl-X/s
- Alternative Name
- Bcl-XS
- Background
- Bcl-XS is the second mRNA species of Bcl-X protein, which encodes a protein that inhibits the ability of Bcl-2 to enhance the survival of growth factor-deprived cells. In vivo, Bcl-XS mRNA is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. Apoptosis was associated with increased protein expression of Bcl-XS, an early marker of apoptosis, and release of Cytochrome C into the cytosol of infected HB cells.
- UniProt
- Q07817
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