ALDH1A1 antibody (AA 283-303)

Catalog No. ABIN3029892

This anti-ALDH1A1 antibody is a Rabbit Polyclonal antibody detecting ALDH1A1 in WB and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for ALDH1A1 antibody (AA 283-303) (ABIN3029892)

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ALDH1A1 Antibody

Binding Specificity: AA 283-303

Purification: Antigen affinity

Immunogen: Amino acids 283-303 (DLDNAVEFAHHGVFYHQGQCC-human) were used as the immunogen for this ALDH1A1 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the ALDH1A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the ALDH1A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for ALDH1A1

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Alternative Name: ALDH1A1

Background: Aldehyde dehydrogenase 1 family, member A1, also called ALDH1, RALDH1 or ALDH, is an enzyme that in humans is encoded by the ALDH1A1 gene. And this protein belongs to the aldehyde dehydrogenases family of proteins. The gene is mapped on 9q21.13. ALDH1A1 also belongs to the group of corneal crystallins that help maintain the transparency of the cornea. It is associated with a low Km for NAD, a high Km for acetaldehyde, and is strongly inactivated by disulfiram. Retinaldehyde is generated by ADH1 from retinol, and its concentration is determined in large part by its subsequent catabolism by ALDH1A1 to retinoic acid.

UniProt: P00352

Pathways: Dopaminergic Neurogenesis