Caveolin 2 antibody (AA 1-17)

Catalog No. ABIN3030339

This anti-Caveolin 2 antibody is a Rabbit Polyclonal antibody detecting Caveolin 2 in WB and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for Caveolin 2 antibody (AA 1-17) (ABIN3030339)

Target: Caveolin 2 (CAV2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Caveolin 2 Antibody

Binding Specificity: AA 1-17

Purification: Antigen affinity

Immunogen: Amino acids 1-17 (MGLETEKADVQLFMDDD-human) were used as the immunogen for this Caveolin-2 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Caveolin-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Caveolin-2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Caveolin 2

Target: Caveolin 2 (CAV2)

Alternative Name: Caveolin-2

Background: Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Both are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury. The CAV2 gene is mapped to 7q31.1-q31.2. The CAV1 gene contains 3 exons, while the human CAV2 gene contains 2 exons. The boundary of the last exon of both are analogous, suggesting that they arose through gene duplication. The genes encoding murine caveolin-1 and -2 are colocalized within the A2 region of mouse chromosome 6.

UniProt: P51636

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development