KLF3 antibody (N-Term)

Catalog No. ABIN3031564

This Rabbit Polyclonal antibody specifically detects KLF3 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for KLF3 antibody (N-Term) (ABIN3031564)

Target: KLF3 (Kruppel-Like Factor 3 (Basic) (KLF3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KLF3 Antibody

Binding Specificity: N-Term

Purification: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human KLF3 (SYPSNYMESMKPNKY) was used as the immunogen for this KLF3 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the KLF3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the KLF3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for KLF3

Target: KLF3 (Kruppel-Like Factor 3 (Basic) (KLF3))

Alternative Name: KLF3

Background: Kruppel-like factor 3 is a protein that in humans is encoded by the KLF3 gene. It is also known as BKLF (Basic kruppel-like factor). KLF3 is a member of the Krüppel-like factors family of transcription factors. It primarily represses transcription through the transcriptional corepressor C-terminal binding protein (CtBP). Suske et al.(2005) stated that the human gene maps to chromosome 4p14, and the mouse gene maps to chromosome 5C3.3. Suske et al.(2005) stated that the human and mouse KLF3 proteins contain 345 and 344 amino acids, respectively. Both have a characteristic zinc finger domain, but lack the N-terminal buttonhead box found in related SP transcription factors. The repression mediated through KLF3 is also partially dependent on the sumoylation of its K10 and K197. Within KLF3's C-terminal, which is highly conserved throughout the KLF family, resides three C2H2 zinc fingers that preferentially bind the site NRG GNG NGR.

UniProt: P57682