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MPG antibody (C-Term)

MPG Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031925
$635.25
Plus shipping costs $45.00
100 μg
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  • Target See all MPG Antibodies
    MPG (N-Methylpurine-DNA Glycosylase (MPG))
    Binding Specificity
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 25
    • 11
    • 10
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 25
    • 2
    Rabbit
    Clonality
    • 25
    • 2
    Polyclonal
    Conjugate
    • 22
    • 2
    • 1
    • 1
    • 1
    This MPG antibody is un-conjugated
    Application
    • 22
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Antigen affinity
    Immunogen
    An amino acid sequence from the C-terminus of human MPG (NKSFDQRDLAQDEAVW) was used as the immunogen for this MPG antibody.
    Isotype
    IgG
  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the MPG antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the MPG antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    MPG (N-Methylpurine-DNA Glycosylase (MPG))
    Alternative Name
    MPG (MPG Products)
    Synonyms
    AAG antibody, ADPG antibody, APNG antibody, CRA36.1 antibody, MDG antibody, Mid1 antibody, PIG11 antibody, PIG16 antibody, anpg antibody, 9830006D05 antibody, AI326268 antibody, Aag antibody, zgc:162984 antibody, MPG antibody, MPGR antibody, N-methylpurine DNA glycosylase antibody, N-methylpurine-DNA glycosylase antibody, MPG antibody, Mpg antibody, mpg antibody, CpB0526 antibody, gll2491 antibody
    Background
    N-Methylpurine-DNA glycosylase is encoded by the MPG gene, mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines. The gene was expressed in all cell lines and tissues examined, but was found at particularly high levels in a colon adenocarcinoma cell line (HT29). The completely characterized human gene was found to span 7 to 8 kb of genomic DNA and to be localized 75 kb upstream of the embryonic zeta-globin gene. To assess the contribution of MPG to the repair of several mutagenic lesions in vivo, Hang et al.(1997) biochemically analyzed cell-free extracts of tissues from mice with a targeted deletion of the gene. Following treatment with DNA-methylating agents, increased persistence of 7-methylguanine (meG) was found in liver sections of MPG knockout mice in comparison with wildtype mice, demonstrating an in vivo phenotype for the MPG-null animals.
    UniProt
    P29372
    Pathways
    DNA Damage Repair
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